Roundup Ready Flex

Roundup Ready Flex cotton

For more information including grower resources and please visit:


To learn more about Roundup Ready flex download a copy of the Weed Resistance Management Plan.

What is Roundup Ready Flex®?

Roundup Ready Flex cotton is a genetically modified crop available in Australia. It contains a modified protein (CP4 EPSPS) that allows Roundup Ready Flex cotton plants to tolerate applications of glyphosate. Two copies of the CP4 EPSPS gene are present and are expressed in both the vegetative and reproductive structures – making Roundup Ready Flex cotton tolerant of glyphosate during squaring, flowering and boll filling.

The herbicide glyphosate interrupts the production of proteins essential for plant survival by inhibiting the production of EPSPS (or 5-enolpyruvylshikimate-3-phosphate Synthase), which is an enzyme involved in converting sugars produced from photosynthesis to amino acids essential for plant survival. Monsanto was able to identify a soil bacterium which produced a modified form of the EPSPS enzyme, the CP4 strain, which was not affected by glyphosate. This modified form of EPSPS is functionally and chemically similar to naturally occurring EPSPS. The modified enzyme allows the production of amino acids and proteins in the presence of glyphosate, which means the modified plant is unaffected by applications of this herbicide. 

For more information about the use of Roundup Ready herbicide with PLANTSHIELD by Monsanto in Roundup Ready Flex crops please visit our Roundup® page.

Why do growers use the Roundup Ready Flex technology?

Roundup Ready Flex cotton offers growers

  • superior and effective broad spectrum weed control
  • wide application window and ability to control weeds where they appear
  • outstanding crop safety when using Roundup Ready herbicide with PLANTSHIELD

By using Roundup Ready Flex technology, growers can control weeds on a ‘needs basis’, reacting to weed flushes that may occur as a result of rainfall or irrigation. Roundup Ready Flex cotton is also an important component of Integrated Weed Management (IWM) strategies in Australian cotton systems. 

The use of Roundup Ready herbicide with PLANTSHIELD should be used in accordance with the product label and a part of sustainable weed management practices. For more information about growing Roundup Ready Flex visit our Stewardship page.

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